Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005928 | 0.90 | HDAC1 (0.35) | KMT2AALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL30006749 | 0.84 | KMT2A (0.45) | KMT2AL3MBTL1ALDH1A1CYP19A1KDM4E | |
| SCHEMBL30006097 | 0.79 | PARP1 (0.38) | KMT2AALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL30006618 | 0.77 | CA1 (0.38) | KMT2AALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL30005739 | 0.77 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1HDAC1GAA | |
| SCHEMBL30964962 | 0.72 | GLS (0.40) | KMT2AL3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14012666 | 0.72 | HSP90AA1 (0.42) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3118579 | 0.71 | GLS (0.39) | KMT2AALDH1A1HTTHDAC1HDAC3 | |
| SCHEMBL3110201 | 0.71 | GLS (0.43) | KMT2AALDH1A1HTTHDAC1HDAC3 | |
| SCHEMBL1323637 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HTTSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |