Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005644 | 0.84 | KMT2A (0.45) | KMT2AALDH1A1L3MBTL1CYP19A1HSD17B10 | |
| SCHEMBL30005739 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1L3MBTL1GAATSHR | |
| SCHEMBL30005618 | 0.76 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1 | |
| SCHEMBL30005928 | 0.74 | HDAC1 (0.35) | KMT2AALDH1A1METAP2CYP19A1 | |
| SCHEMBL16269680 | 0.72 | ATM (0.48) | KMT2AALDH1A1L3MBTL1FPR3FPR2 | |
| SCHEMBL7808421 | 0.72 | KDM4E (0.42) | ALDH1A1FPR3FPR2HSD17B10KDM4E | |
| SCHEMBL30004674 | 0.72 | ALDH1A1 (0.46) | KMT2AALDH1A1L3MBTL1CYP19A1GAA | |
| SCHEMBL12286676 | 0.72 | ALDH1A1 (0.44) | KMT2AALDH1A1L3MBTL1FPR3FPR2 | |
| SCHEMBL14535359 | 0.71 | CYP1A2 (0.46) | KMT2AFPR3FPR2KDM4EHPGD | |
| SCHEMBL3919913 | 0.71 | FPR3 (0.39) | FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |