Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.63 |
| ▸ | CA9 | Q16790 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923940 | 0.82 | CA12 (0.71) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL1395581 | 0.81 | ALDH1A1 (0.50) | CA12CA9SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1924309 | 0.77 | CA12 (0.72) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL13320282 | 0.75 | CA12 (0.79) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL8885028 | 0.74 | CA12 (0.74) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL8887751 | 0.73 | CA12 (0.74) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL3336990 | 0.73 | CA12 (1.00) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL26212219 | 0.73 | CA12 (0.71) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL9490269 | 0.72 | CA12 (0.97) | CA12CA9SMN1; SMN2TSHRCA1 | |
| SCHEMBL6595668 | 0.72 | ALDH1A1 (0.62) | SMN1; SMN2TSHRALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |