Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860219 | 0.91 | LOXL2 (0.64) | LOXL2HRH3MTNR1AMTNR1B | |
| SCHEMBL3195577 | 0.89 | LOXL2 (0.58) | LOXL2HRH3IDO1MTNR1AMTNR1B | |
| SCHEMBL25444786 | 0.83 | GPR84 (0.45) | HRH3GPR84 | |
| SCHEMBL7169246 | 0.82 | LOXL2 (0.69) | LOXL2HRH3MTNR1AMTNR1B | |
| SCHEMBL31059889 | 0.82 | LOXL2 (0.69) | LOXL2HRH3MTNR1AMTNR1B | |
| SCHEMBL4075676 | 0.81 | HRH3 (0.52) | LOXL2HRH3IDO1 | |
| SCHEMBL28335219 | 0.81 | LOXL2 (0.67) | LOXL2HRH3MTNR1AMTNR1B | |
| SCHEMBL2071314 | 0.80 | LOXL2 (0.56) | LOXL2HRH3IDO1MTNR1AMTNR1B | |
| SCHEMBL3193911 | 0.80 | BCHE (0.56) | LOXL2HRH3MTNR1AMTNR1B | |
| SCHEMBL6026168 | 0.80 | LOXL2 (0.56) | LOXL2HRH3MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559974-B | Seven-membered ring fused cyclopenta [ b ] indole derivative and synthesis method and application thereof | 华东师范大学 | 2022-10-25 | — | — | CN | disclosed |