Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006605 | 0.91 | TRPV4 (0.57) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005407 | 0.88 | HTT (0.55) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005576 | 0.87 | TRPV4 (0.55) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005706 | 0.86 | ALDH1A1 (0.66) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005867 | 0.86 | TRPV4 (0.54) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005897 | 0.86 | ALDH1A1 (0.55) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005315 | 0.84 | TRPV4 (0.53) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL23217100 | 0.84 | MAPT (0.70) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30006441 | 0.84 | MAPT (0.60) | TRPV4HTTMAPTLMNAGAA | |
| SCHEMBL30005773 | 0.84 | TRPV4 (0.50) | TRPV4HTTMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |