SCHEMBL30005976

SCHEMBL30005976

CC(=O)Nc1cc(F)ccc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.50
HDAC1 Q13547 4/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
HDAC6 Q9UBN7 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 4/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
CCNA1 P78396 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC2 Q92769 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
RAB9A P51151 3/20 0.43
DYRK1A Q13627 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375020 1.00 RXFP1 (0.50) RXFP1HDAC1CA1CA2CA9
SCHEMBL422893 0.85 CA1 (0.58) RXFP1HDAC1CA1CA2CA9
SCHEMBL30559973 0.85 CA1 (0.58) RXFP1HDAC1CA1CA2CA9
SCHEMBL1704181 0.83 ALDH1A1 (0.44) HDAC1HDAC6SMN1; SMN2GAAALDH1A1
SCHEMBL20560249 0.81 ALOX15 (0.43) HDAC1HDAC6SMN1; SMN2GAAALDH1A1
SCHEMBL30748254 0.81 SMN1; SMN2 (0.55) HDAC1CA1CA2CA9HDAC6
SCHEMBL8955980 0.81 SMN1; SMN2 (0.55) HDAC1CA1CA2CA9HDAC6
SCHEMBL3715354 0.81 ALDH1A1 (0.58) RXFP1HDAC1CA1CA2CA9
SCHEMBL28355716 0.81 KMT2A (0.46) SMN1; SMN2GAAALDH1A1POLBMEN1
SCHEMBL1282557 0.81 PDK1 (0.45) CA1CA2CA9GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694935-A1 COMBINATION OF ANTIBODY-DRUG CONJUGATE AND ANTI-PD-1 ANTIBODY, AND USE THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2026-02-18 EP disclosed
EP-4688871-A1 SITE-SPEICFIC ORTHOGONAL BIOCONJUGATE MODALITY AND APPLICATION THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2026-02-11 EP disclosed
EP-4554956-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2025-05-21 EP disclosed
EP-4554626-A2 ANTI-TROP2 ANTIBODY AND CONJUGATE THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2025-05-21 EP disclosed
EP-4547285-A1 ANTI-FGFR3 ANTIBODY CONJUGATE AND MEDICAL USE THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2025-05-07 EP disclosed
CN-119630427-A Anti-FGFR 3 antibody conjugates and medical uses thereof 启德医药科技(苏州)有限公司 2025-03-14 CN disclosed
CN-119497717-A Linker, conjugate and uses thereof 启德医药科技(苏州)有限公司 2025-02-21 CN disclosed
CN-119462943-A Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技(苏州)有限公司 2025-02-18 CN disclosed
WO-2024213091-A9 COMBINATION OF ANTIBODY-DRUG CONJUGATE AND ANTI-PD-1 ANTIBODY, AND USE THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2024-12-19 WO disclosed
CN-118251241-B Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技(苏州)有限公司 2024-12-13 CN disclosed
WO-2024012569-A9 LINKERS, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2024-03-28 WO disclosed
WO-2024012566-A2 ANTIBODY, LINKERS, PAYLOAD, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2024-01-18 WO disclosed
WO-2024012569-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2024-01-18 WO disclosed
WO-2024002154-A1 ANTI-FGFR3 ANTIBODY CONJUGATE AND MEDICAL USE THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2024-01-04 WO disclosed
CN-115990269-B Esatitecan derivatives and linker-carriers and conjugates thereof 启德医药科技(苏州)有限公司 2023-11-14 CN disclosed
CN-112771046-B Other substituted triazoloquinoxaline derivatives 格吕伦塔尔有限公司 2023-09-19 CN disclosed
EP-4211145-A1 EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2023-07-19 EP disclosed
WO-2023088235-A1 EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-05-25 WO disclosed
CN-115990269-A Esatitecan derivatives and linker-carriers and conjugates thereof 启德医药科技(苏州)有限公司 2023-04-21 CN disclosed
EP-4090660-A1 QUINOXALINE DERIVATIVES Grünenthal GmbH (DE) 2022-11-23 EP disclosed