Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | PRKCB | P05771 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | PRKCH | P24723 | 2/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648082 | 1.00 | KDM4E (0.44) | KDM4EMEN1KMT2AHTR6OPRL1 | |
| SCHEMBL19869852 | 0.78 | HTR3A (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL18612963 | 0.77 | PTGDR2 (0.51) | KDM4EMEN1KMT2AHTR6OPRL1 | |
| SCHEMBL28094853 | 0.77 | KDM4E (0.44) | KDM4EMEN1KMT2AHTR6OPRL1 | |
| SCHEMBL23648384 | 0.76 | OPRM1 (0.36) | KDM4EMEN1KMT2AOPRL1OPRM1 | |
| SCHEMBL20604757 | 0.75 | HTR3A (0.37) | OPRL1OPRM1OPRK1OPRD1CAMK2B | |
| SCHEMBL24117781 | 0.73 | OPRL1 (0.48) | KDM4EMEN1KMT2AOPRL1OPRM1 | |
| SCHEMBL21600837 | 0.73 | OPRL1 (0.54) | KDM4EMEN1KMT2AHTR6OPRL1 | |
| SCHEMBL28914516 | 0.73 | OPRL1 (0.48) | KDM4EMEN1KMT2AHTR6OPRL1 | |
| SCHEMBL18593489 | 0.73 | HTR6 (0.46) | KDM4EMEN1KMT2AHTR6OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |