Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 16/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 15/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092754 | 1.00 | CHRM3 (0.53) | CHRM3CHRM2OPRM1SIGMAR1MEN1 | |
| SCHEMBL4762750 | 0.86 | ALDH1A1 (0.43) | OPRM1SIGMAR1 | |
| SCHEMBL19873844 | 0.86 | OPRD1 (0.43) | OPRM1 | |
| SCHEMBL3063074 | 0.84 | RPLP1 (0.38) | CHRM3CHRM2MEN1KMT2A | |
| SCHEMBL1285381 | 0.83 | SMN1; SMN2 (0.54) | MEN1KMT2A | |
| SCHEMBL2490671 | 0.82 | POLB (0.43) | CHRM3CHRM2OPRM1 | |
| SCHEMBL27769658 | 0.80 | ALDH1A1 (0.39) | OPRM1MEN1KMT2A | |
| SCHEMBL4767301 | 0.77 | CXCR2 (0.38) | — | |
| SCHEMBL4564976 | 0.76 | SLC6A15 (0.44) | MEN1KMT2A | |
| SCHEMBL10674708 | 0.76 | OPRM1 (0.68) | CHRM3CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323357-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | Siegfried AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022218811-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | SIEGFRIED AG (CH) | 2022-10-20 | — | — | WO | disclosed |
| EP-4074712-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | Siegfried AG (CH) | 2022-10-19 | — | — | EP | disclosed |