Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624298 | 1.00 | GAA (0.33) | GAAMAPTRAPGEF3RAPGEF4KDM1A | |
| SCHEMBL20680925 | 0.78 | ADRB2 (0.31) | — | |
| SCHEMBL20681213 | 0.74 | GAA (0.34) | GAAMAPTKDM1AKCNH2KDM1B | |
| SCHEMBL30006278 | 0.74 | GAA (0.34) | GAAMAPTKDM1AKCNH2KDM1B | |
| SCHEMBL31506853 | 0.71 | KDM1A (0.38) | MAPTKDM1AKCNH2KDM1B | |
| SCHEMBL29526302 | 0.69 | CHRNB2 (0.33) | — | |
| SCHEMBL26181305 | 0.69 | CHRNB2 (0.33) | — | |
| SCHEMBL23320042 | 0.69 | MAOA (0.31) | — | |
| SCHEMBL16905117 | 0.69 | AHR (0.32) | MAPT | |
| SCHEMBL25200808 | 0.68 | ACHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771046-B | Other substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |