SCHEMBL3000798

SCHEMBL3000798

O=C(O)CN1CCN(CC(=O)O)CC(Cc2ccccc2)N(CC(=O)O)CC1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.44
DPP4 P27487 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858941 1.00 FOLH1 (0.44) FOLH1DPP4
SCHEMBL19590904 0.90 DPP4 (0.43) FOLH1DPP4
SCHEMBL23504903 0.90 FOLH1 (0.43) FOLH1DPP4
SCHEMBL9032439 0.89 FOLH1 (0.45) FOLH1DPP4
SCHEMBL18840376 0.88 FOLH1 (0.45) FOLH1DPP4
SCHEMBL16645333 0.88 L3MBTL1 (0.45) FOLH1DPP4
SCHEMBL1079200 0.88 FOLH1 (0.45) FOLH1DPP4
SCHEMBL19447720 0.88 L3MBTL1 (0.45) FOLH1DPP4
SCHEMBL16645337 0.88 L3MBTL1 (0.45) FOLH1DPP4
SCHEMBL1996255 0.88 FOLH1 (0.45) FOLH1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3570897-B1 RADIOIMMUNOCONJUGATE FOR USE IN TREATING BONE MARROW ASSOCIATED DISEASES THERAPHARM GMBH (CH) 2023-10-04 EP claimed
US-20220401594-A1 RADIOIMMUNOCONJUGATE FOR USE IN TREATING BONE MARROW ASSOCIATED DISEASES THERAPHARM GMBH (CH) 2022-12-22 US claimed
US-20100183505-A1 IMMUNOCONJUGATE FOR HUMAN CD66 FOR THE TREATMENT OF MULTIPLE MYELOMA AND OTHER HAEMATOLOGICAL MALIGNANCIES THERAPHARM GMBH 2010-07-22 US claimed
EP-3570897-B1 RADIOIMMUNOCONJUGATE FOR USE IN TREATING BONE MARROW ASSOCIATED DISEASES THERAPHARM GMBH (CH) 2023-10-04 EP disclosed
US-20220401594-A1 RADIOIMMUNOCONJUGATE FOR USE IN TREATING BONE MARROW ASSOCIATED DISEASES THERAPHARM GMBH (CH) 2022-12-22 US disclosed
EP-3222617-B1 PSMA-TARGETING COMPOUNDS AND USES THEREOF UNIV JOHNS HOPKINS (US) 2022-07-06 EP disclosed
US-20210308207-A1 COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY TAGWORKS PHARMACEUTICALS B.V. (NL) 2021-10-07 US disclosed
US-9072797-B2 Immunoconjugate for human CD66 for the treatment of multiple myeloma and other haematological malignancies THERAPHARM GMBH (CH) 2015-07-07 US disclosed
US-20100183505-A1 IMMUNOCONJUGATE FOR HUMAN CD66 FOR THE TREATMENT OF MULTIPLE MYELOMA AND OTHER HAEMATOLOGICAL MALIGNANCIES THERAPHARM GMBH 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401594-A1 RADIOIMMUNOCONJUGATE FOR USE IN TREATING BONE MARROW ASSOCIATED DISEASES FCGR2A, FCGR3B, BST2 FOLH1 867/4885DPP4 3770/4885
US-20100183505-A1 IMMUNOCONJUGATE FOR HUMAN CD66 FOR THE TREATMENT OF MULTIPLE MYELOMA AND OTHER HAEMATOLOGICAL MALIGNANCIES CD63, CD47, CD22 FOLH1 294/4885DPP4 3039/4885
US-20210308207-A1 COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY VIP, PIN1, QPCT FOLH1 113/4885DPP4 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.