Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123464 | 1.00 | NPC1 (0.48) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL3123458 | 1.00 | NPC1 (0.48) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL14963072 | 1.00 | NPC1 (0.48) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL26478601 | 0.87 | MAPT (0.43) | MAPTKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL2011458 | 0.83 | KMT2A (0.40) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL11960797 | 0.83 | KMT2A (0.40) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL3662033 | 0.83 | RAB9A (0.44) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL3662035 | 0.83 | RAB9A (0.44) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL17253032 | 0.83 | MET (0.47) | NPC1RAB9AMAPTKMT2AGFER | |
| SCHEMBL1796296 | 0.82 | LMNA (0.41) | NPC1RAB9AMAPTKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004816-A | Isoxazoline derivatives | 礼蓝动物保健有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115210221-B | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118047728-B | Preparation method of fluororalrana | 南京道尔医药研究院有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118047728-A | Preparation method of fluororalrana | 南京道尔医药研究院有限公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-4355735-A1 | ISOXAZOLINE PESTICIDES | Elanco Tiergesundheit AG (CH) | 2024-04-24 | — | — | EP | disclosed |
| CN-117529473-A | Isoxazoline insecticides | 礼蓝动物保健有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117500800-A | (thio) oxazoline insecticide | 礼蓝动物保健有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022263573-A1 | ISOXAZOLINE PESTICIDES | ELANCO TIERGESUNDHEIT AG (US) | 2022-12-22 | — | — | WO | disclosed |
| CN-115210221-A | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2022-10-18 | — | — | CN | disclosed |