Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662035 | 1.00 | RAB9A (0.44) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18835536 | 0.88 | RAB9A (0.44) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18835535 | 0.88 | RAB9A (0.44) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL15878745 | 0.84 | SMN1; SMN2 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL15878746 | 0.84 | SMN1; SMN2 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14727929 | 0.84 | SMN1; SMN2 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3123464 | 0.83 | NPC1 (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14963072 | 0.83 | NPC1 (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30008909 | 0.83 | NPC1 (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3123458 | 0.83 | NPC1 (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623896-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2592079-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2013-05-15 | — | — | EP | disclosed |
| EP-2518068-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-2238132-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2238132-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | RAB9A 144/4885NPC1 732/4885KMT2A 2962/4885 |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | RAB9A 140/4885NPC1 730/4885KMT2A 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.