Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | FNTA | P49354 | 1/20 | 0.64 |
| ▸ | FNTB | P49356 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | TP53 | P04637 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009654 | 0.94 | MAPT (0.67) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30010237 | 0.92 | MAPT (0.67) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30010272 | 0.92 | MAPT (0.57) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30010517 | 0.92 | MAPT (0.64) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30009979 | 0.91 | MAPT (0.58) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30009805 | 0.90 | MAPT (0.57) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL30010877 | 0.89 | MEN1 (0.65) | RXFP1MEN1KMT2AFNTAFNTB | |
| SCHEMBL7571584 | 0.79 | SLC40A1 (0.66) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL7569885 | 0.77 | ALDH1A1 (0.59) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL28384243 | 0.76 | KEAP1 (0.57) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111067889-B | Application of 2-methyl naphtho [1,2-b ] furan compound in preparation of medicine related to diabetic nephropathy | 徐州医科大学 | 2022-11-18 | — | — | CN | disclosed |