Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569885 | 0.83 | ALDH1A1 (0.59) | SLC40A1TSHRKMT2AMEN1GAA | |
| SCHEMBL5072751 | 0.83 | MEN1 (0.71) | SLC40A1KCNA5KMT2AMEN1GAA | |
| SCHEMBL7388562 | 0.82 | MEN1 (0.70) | SLC40A1KCNA5KMT2AMEN1GAA | |
| SCHEMBL5074828 | 0.82 | MEN1 (0.70) | SLC40A1KCNA5KMT2AMEN1GAA | |
| SCHEMBL2702444 | 0.81 | ALDH1A1 (0.79) | KMT2AMEN1GAAALDH1A1HPGD | |
| SCHEMBL11973518 | 0.80 | SLC40A1 (1.00) | SLC40A1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL30009985 | 0.79 | RXFP1 (0.67) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL6822984 | 0.78 | ALDH1A1 (0.60) | TSHRKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7318545 | 0.78 | POLB (0.55) | TSHRGAAALDH1A1POLBHPGD | |
| SCHEMBL5074801 | 0.78 | KCNA5 (1.00) | SLC40A1KCNA5KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |