Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 7/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153790 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27150060 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL4470355 | 0.84 | ITGB3 (0.58) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27120520 | 0.82 | ALDH1A1 (0.45) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27121292 | 0.82 | GPR119 (0.45) | GNAI3GNAO1GNAI1 | |
| SCHEMBL27153788 | 0.82 | GPR119 (0.45) | GNAI3GNAO1GNAI1 | |
| SCHEMBL30015039 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL30014967 | 0.81 | CACNA2D1 (0.39) | ITGB3ITGA2BGNAO1F2RTPSAB1 | |
| SCHEMBL30014708 | 0.81 | ITGB3 (0.68) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL7452238 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2BGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223034-A1 | SOS1 DEGRADATION AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022223033-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022223039-A1 | SOS1 DEGRADER, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |