Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RHOA | P61586 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206895 | 1.00 | ALOX5 (0.68) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL1206897 | 1.00 | ALOX5 (0.68) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11175049 | 0.98 | ALOX5 (0.67) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL9380275 | 0.91 | KDM4E (0.59) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL9380269 | 0.91 | KDM4E (0.59) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL7332640 | 0.90 | ALOX5 (0.68) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8494290 | 0.90 | ALOX5 (0.68) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8783371 | 0.89 | ALDH1A1 (0.57) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL28893713 | 0.89 | ALDH1A1 (0.57) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL9379839 | 0.89 | THRB (0.64) | ALOX5PTGS1PTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553069-A1 | ALPHA,ß-UNSATURATED AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-119790041-A | Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-04-08 | — | — | CN | disclosed |
| CN-115368263-B | Synthesis and pharmaceutical application of cinnamic acid amide derivative | 南开大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-117402123-A | Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-01-16 | — | — | CN | disclosed |
| CN-112204018-B | Acrylic compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |
| CN-115368263-A | Synthesis of cinnamic acid amide derivative and pharmaceutical application thereof | 南开大学 | 2022-11-22 | — | — | CN | disclosed |