Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 5/20 | 0.69 |
| ▸ | PTPRC | P08575 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016005 | 0.91 | PTPRC (0.68) | PTPRGPTPRCKMT2AMEN1ALDH1A1 | |
| SCHEMBL11818393 | 0.88 | KMT2A (0.60) | PTPRGPTPRCKMT2AMEN1PTGDR2 | |
| SCHEMBL11817650 | 0.81 | PTPRG (0.76) | PTPRGPTPRCKMT2AMEN1AR | |
| SCHEMBL28109773 | 0.79 | KMT2A (0.64) | PTPRGPTPRCKMT2AMEN1ALDH1A1 | |
| SCHEMBL18769941 | 0.79 | PTPRC (0.54) | PTPRGPTPRCKMT2AMEN1PTGDR2 | |
| SCHEMBL30016479 | 0.79 | PTPRC (0.54) | PTPRGPTPRCKMT2AMEN1PTGDR2 | |
| SCHEMBL11815274 | 0.77 | MRGPRX4 (0.53) | PTPRGPTPRCKMT2AMEN1PTGDR2 | |
| SCHEMBL17495183 | 0.76 | PTPRC (0.57) | PTPRGPTPRCKMT2AMEN1CYP1A2 | |
| SCHEMBL17927526 | 0.76 | PTPRC (0.51) | PTPRGPTPRCKMT2AMEN1ALDH1A1 | |
| SCHEMBL29295506 | 0.76 | L3MBTL1 (0.52) | PTPRGPTPRCKMT2AMEN1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |