Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010458 | 0.89 | SLC1A3 (0.47) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL22605486 | 0.82 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6265164 | 0.82 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL16596492 | 0.82 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL30137666 | 0.82 | SLC1A3 (0.46) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| Norharmane SCHEMBL28917524 | 0.81 | GABRP (0.43) | SLC15A1ALDH1A1KMT2ATDP1LMNA | |
| SCHEMBL27713444 | 0.81 | SLC15A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL7410438 | 0.80 | SLC1A3 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL30020534 | 0.79 | SLC1A3 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL30011033 | 0.79 | SLC1A3 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477683-A | Dioxiexacyclo-tetrahydrocarboline-3-formylamino acid with interleukin-6 as target and preparation and application thereof | 首都医科大学 | 2022-12-16 | — | — | CN | disclosed |