Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596492 | 1.00 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL2860601 | 0.86 | SLC15A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL17210678 | 0.84 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL30020515 | 0.82 | SLC15A1 (0.52) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| Hydrochloric Acid SCHEMBL27518479 | 0.81 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| Hydrochloric Acid SCHEMBL19511476 | 0.81 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL6546883 | 0.81 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A3 | |
| SCHEMBL10047603 | 0.81 | ALDH1A1 (0.54) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL9792708 | 0.81 | ALDH1A1 (0.54) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL17483756 | 0.81 | ALDH1A1 (0.54) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529030-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | Prestwick Pharmaceuticals, Inc. (US) | 2005-05-11 | — | — | EP | claimed |
| WO-2004016580-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | PRESTWICK PHARMACEUTICALS, INC. (US) | 2004-02-26 | — | — | WO | claimed |
| US-20120202243-A1 | IN Vivo Incorporation of Unnatural Amino Acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-09 | — | — | US | disclosed |
| US-8173392-B2 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-05-08 | — | — | US | disclosed |
| US-8012739-B2 | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA synthetase pairs | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090227002-A1 | Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs | THE SCRIPPS RESEARCH INSTITUTE and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-10 | — | — | US | disclosed |
| US-20090068717-A1 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1529030-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | Prestwick Pharmaceuticals, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004016580-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | PRESTWICK PHARMACEUTICALS, INC. (US) | 2004-02-26 | — | — | WO | disclosed |