Phenol

Phenol

SCHEMBL3002830

Cc1cc(Cc2cc(C)c(O)c(C)c2)cc(C)c1O.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.53
CXCL12 P48061 1/20 0.53
SHBG P04278 1/20 0.52
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
TTR P02766 1/20 0.47
ALOX5 P09917 1/20 0.47
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
GLA P06280 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA9 Q16790 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL15239719 1.00 HMGB1 (0.53) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL9480008 0.89 HMGB1 (0.55) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL5527320 0.85 ESR1 (0.61) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL68876 0.84 SHBG (0.67) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL28096899 0.84 IDH1 (0.49) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL1176784 0.82 ESR1 (0.60) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL1121332 0.82 SHBG (0.64) HMGB1CXCL12SHBGPTGS1PTGS2
SCHEMBL2166973 0.81 ESR1 (0.54) HMGB1CXCL12SHBGPTGS1PTGS2
Phenol SCHEMBL7039341 0.80 CA1 (0.67) PTGS1PTGS2TTRALOX5ESR2
SCHEMBL10427465 0.80 SHBG (0.57) HMGB1CXCL12SHBGPTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7786219-B2 Cyanate-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-08-31 US disclosed
US-20100048826-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2010-02-25 US disclosed
US-7632912-B2 Carboxylic acid-modified bisphenol epoxy di(meth)acrylate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-12-15 US disclosed
US-20090205856-A1 Carboxylic Acid-Modified Bisphenol Epoxy Di(meth)acrylate ISHII KENJI 2009-08-20 US disclosed
US-7560518-B2 (Meth)acrylated epoxy-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-07-14 US disclosed
US-20080269427-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2008-10-30 US disclosed
US-7393904-B2 (Meth)acrylate-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-07-01 US disclosed
US-20080033117-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2008-02-07 US disclosed
US-7276563-B2 Polyphenylene ether oligomer compound, derivatives thereof and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-10-02 US disclosed
US-20050065241-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI (JP) 2005-03-24 US disclosed
US-6835785-B2 Curable end groups, such as allyl, (meth)acryloyloxy, glycidyloxy and cyanate groups; printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-12-28 US disclosed
US-20030194562-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090205856-A1 Carboxylic Acid-Modified Bisphenol Epoxy Di(meth)acrylate EED, MMAB, CAD HMGB1 1162/4885CXCL12 4604/4885SHBG 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.