Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234101 | 0.84 | BCAT2 (0.59) | EIF4ERORBPTGER1PTGER3PTGER2 | |
| SCHEMBL27922052 | 0.79 | MAPK14 (0.47) | EIF4ERORBMAPK14AHRMKNK1 | |
| SCHEMBL30030003 | 0.78 | BCAT2 (0.50) | BCAT2MKNK1MKNK2PARP1IKBKB | |
| SCHEMBL8102370 | 0.77 | BCAT2 (0.69) | BCAT2PARP1IKBKBKMT2ANPC1 | |
| SCHEMBL28053360 | 0.76 | BCAT2 (0.49) | BCAT2IKBKBKMT2ANPC1MAPT | |
| SCHEMBL28139759 | 0.75 | ALDH1A1 (0.47) | PARP1KMT2AATMNPC1MAPT | |
| SCHEMBL30213820 | 0.75 | ALDH1A1 (0.47) | PARP1KMT2AATMNPC1MAPT | |
| SCHEMBL28170993 | 0.74 | PTGER1 (0.48) | EIF4ERORBPTGER1PTGER3PTGER2 | |
| SCHEMBL5381730 | 0.72 | PTGER1 (0.53) | EIF4ERORBPTGER1PTGER3PTGER2 | |
| SCHEMBL3542609 | 0.72 | PTGER1 (0.56) | EIF4ERORBPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831302-B | Benzisoselenazolone derivative and preparation method and application thereof | 山东大学 | 2022-11-29 | — | — | CN | disclosed |