Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666608 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL30028995 | 0.82 | METAP2 (0.50) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL28665824 | 0.82 | METAP2 (0.50) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL10501892 | 0.77 | METAP2 (0.66) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL10502469 | 0.76 | METAP2 (0.59) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL30573258 | 0.74 | METAP2 (0.45) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL30573251 | 0.73 | METAP2 (0.74) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| SCHEMBL10501872 | 0.71 | METAP2 (0.62) | ALDH1A1MAPTPOLBMETAP2MEN1 | |
| 4-Nitroaniline SCHEMBL16451 | 0.66 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9065915 | 0.66 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831302-B | Benzisoselenazolone derivative and preparation method and application thereof | 山东大学 | 2022-11-29 | — | — | CN | disclosed |