Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783127 | 1.00 | GPR119 (0.41) | GPR119SMN1; SMN2ESR2USP30LMNA | |
| SCHEMBL23783227 | 0.89 | GPR119 (0.42) | GPR119SMN1; SMN2USP30LMNAHRH3 | |
| SCHEMBL29554597 | 0.89 | GPR119 (0.42) | GPR119SMN1; SMN2USP30LMNAHRH3 | |
| SCHEMBL29554722 | 0.86 | ALDH1A1 (0.48) | LMNATHRBMAPT | |
| SCHEMBL30255294 | 0.86 | ALDH1A1 (0.48) | LMNATHRBMAPT | |
| SCHEMBL25845922 | 0.86 | ALDH1A1 (0.48) | LMNATHRBMAPT | |
| SCHEMBL30255427 | 0.86 | ALDH1A1 (0.48) | LMNATHRBMAPT | |
| SCHEMBL23783155 | 0.84 | GPR119 (0.46) | GPR119 | |
| SCHEMBL30032767 | 0.84 | GPR119 (0.46) | GPR119 | |
| SCHEMBL31342395 | 0.82 | STS (0.42) | GPR119USP30MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823124-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115279370-B | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-4114392-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |