SCHEMBL23783155

SCHEMBL23783155

CC(C)(C)OC(=O)N1CCC(N2CCN(c3ccc(OCc4ccccc4)cc3F)CC2)C(F)(F)C1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 7/20 0.46
▸ YAP1 P46937 3/20 0.46
▸ PRMT5 O14744 3/20 0.42
▸ STS P08842 1/20 0.42
▸ GHSR Q92847 3/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA5B Q9Y2D0 1/20 0.41
▸ GRM5 P41594 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032767 1.00 GPR119 (0.46) GPR119YAP1PRMT5STSGHSR
SCHEMBL30031402 0.84 GPR119 (0.41) GPR119
SCHEMBL23783127 0.84 GPR119 (0.41) GPR119
SCHEMBL8221363 0.84 GPR119 (0.53) GPR119YAP1CA12CA1CA2
SCHEMBL30032071 0.83 CCNT1 (0.38) GPR119YAP1PRMT5STS
SCHEMBL23783137 0.83 CCNT1 (0.38) GPR119YAP1PRMT5STS
SCHEMBL23783305 0.82 TLR9 (0.37) GPR119YAP1PRMT5STSGRM5
SCHEMBL30031986 0.82 TLR9 (0.37) GPR119YAP1PRMT5STSGRM5
SCHEMBL23783227 0.82 GPR119 (0.42) GPR119
SCHEMBL29554597 0.82 GPR119 (0.42) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2025-03-13 — — US disclosed
US-12157735-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-12-03 — — US disclosed
US-12049464-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-07-30 — — US disclosed
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2024-02-15 — — US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 — — US disclosed
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-02 — — US disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 — — EP disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 — — CN disclosed
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2022-03-31 — — US disclosed
WO-2021178920-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2021-09-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-12157735-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-12049464-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 GPR119 2909/4885YAP1 1191/4885PRMT5 2344/4885
US-11691972-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 GPR119 3145/4885YAP1 1955/4885PRMT5 2374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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