SCHEMBL30032767

SCHEMBL30032767

CC(C)(C)OC(=O)N1CCC(N2CCN(c3ccc(OCc4ccccc4)cc3F)CC2)C(F)(F)C1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 7/20 0.46
▸ YAP1 P46937 3/20 0.46
▸ PRMT5 O14744 3/20 0.42
▸ STS P08842 1/20 0.42
▸ GHSR Q92847 3/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA5B Q9Y2D0 1/20 0.41
▸ GRM5 P41594 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23783155 1.00 GPR119 (0.46) GPR119YAP1PRMT5STSGHSR
SCHEMBL30031402 0.84 GPR119 (0.41) GPR119
SCHEMBL23783127 0.84 GPR119 (0.41) GPR119
SCHEMBL8221363 0.84 GPR119 (0.53) GPR119YAP1CA12CA1CA2
SCHEMBL30032071 0.83 CCNT1 (0.38) GPR119YAP1PRMT5STS
SCHEMBL23783137 0.83 CCNT1 (0.38) GPR119YAP1PRMT5STS
SCHEMBL23783305 0.82 TLR9 (0.37) GPR119YAP1PRMT5STSGRM5
SCHEMBL30031986 0.82 TLR9 (0.37) GPR119YAP1PRMT5STSGRM5
SCHEMBL23783227 0.82 GPR119 (0.42) GPR119
SCHEMBL29554597 0.82 GPR119 (0.42) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 — — CN disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 — — CN disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 — — EP disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 — — CN disclosed
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