Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783305 | 1.00 | TLR9 (0.37) | TLR9TLR7GPR119STSACHE | |
| SCHEMBL30032071 | 0.85 | CCNT1 (0.38) | TLR9TLR7GPR119STSACHE | |
| SCHEMBL23783137 | 0.85 | CCNT1 (0.38) | TLR9TLR7GPR119STSACHE | |
| SCHEMBL25846237 | 0.83 | HRH4 (0.35) | TLR9TLR7GRM5 | |
| SCHEMBL23783155 | 0.82 | GPR119 (0.46) | GPR119STSPRMT5YAP1GRM5 | |
| SCHEMBL30032767 | 0.82 | GPR119 (0.46) | GPR119STSPRMT5YAP1GRM5 | |
| SCHEMBL30898917 | 0.82 | PRMT5 (0.38) | TLR9TLR7GPR119STSACHE | |
| SCHEMBL30796953 | 0.81 | STS (0.38) | TLR9TLR7GPR119STSPRMT5 | |
| SCHEMBL27449599 | 0.81 | STS (0.38) | TLR9TLR7GPR119STSPRMT5 | |
| SCHEMBL31639462 | 0.80 | TLR9 (0.46) | TLR9TLR7GPR119ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823124-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115279370-B | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-4114392-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |