SCHEMBL30032071

SCHEMBL30032071

CC(C)(C)OC(=O)N1CCC(N2CCN(c3ccc(Nc4ccc(OCc5ccccc5)nc4OCc4ccccc4)cc3F)CC2)C(F)(F)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNT1 O60563 1/20 0.38
▸ CCNA2 P20248 1/20 0.38
▸ CDK2 P24941 1/20 0.38
▸ CDK9 P50750 1/20 0.38
▸ CCNA1 P78396 1/20 0.38
▸ TLR9 Q9NR96 2/20 0.37
▸ TLR7 Q9NYK1 2/20 0.37
▸ STS P08842 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ SLC2A1 P11166 1/20 0.36
▸ EGFR P00533 2/20 0.36
▸ YAP1 P46937 3/20 0.36
▸ LMNA P02545 2/20 0.36
▸ TP53 P04637 1/20 0.36
▸ GPR119 Q8TDV5 3/20 0.35
▸ BRD4 O60885 2/20 0.35
▸ PRMT5 O14744 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23783137 1.00 CCNT1 (0.38) CCNT1CCNA2CDK2CDK9CCNA1
SCHEMBL28901669 0.92 EGFR (0.37) EGFRMEN1MAPTKMT2A
SCHEMBL25583973 0.88 CCNT1 (0.46) CCNT1CCNA2CDK2CDK9CCNA1
SCHEMBL23783305 0.85 TLR9 (0.37) TLR9TLR7STSACHEYAP1
SCHEMBL30031986 0.85 TLR9 (0.37) TLR9TLR7STSACHEYAP1
SCHEMBL23783155 0.83 GPR119 (0.46) STSYAP1GPR119PRMT5
SCHEMBL30032767 0.83 GPR119 (0.46) STSYAP1GPR119PRMT5
SCHEMBL25846238 0.82 AXL (0.35) CCNT1CDK2CDK9EGFRMEN1
SCHEMBL30898917 0.82 PRMT5 (0.38) CCNT1CCNA2CDK2CDK9CCNA1
SCHEMBL30796702 0.81 STS (0.40) CCNT1CCNA2CDK2CDK9CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 — — CN disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 — — CN disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 — — EP disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 — — CN disclosed
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