Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 6/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034350 | 0.89 | NPEPPS (0.42) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30032902 | 0.87 | HSP90AA1 (0.48) | NPEPPSKDM4EHTTHSP90AA1DDR1 | |
| SCHEMBL30034171 | 0.82 | NPEPPS (0.43) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL31509793 | 0.81 | NPEPPS (0.57) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30032168 | 0.81 | NPEPPS (0.49) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30033042 | 0.81 | KDM4E (0.57) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30034581 | 0.81 | HSD17B10 (0.58) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30033426 | 0.81 | NPEPPS (0.43) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30033413 | 0.79 | KIF11 (0.46) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30032960 | 0.79 | HSP90AA1 (0.36) | HSP90AA1CYP11B2BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |