Decursinol

Decursinol

SCHEMBL30034733

CC1(C)Oc2cc3oc(=O)ccc3cc2C[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 5/20 1.00
▸ ACHE P22303 4/20 1.00
▸ MGAM O43451 1/20 1.00
▸ SI P14410 1/20 1.00
▸ PTPN1 P18031 1/20 1.00
▸ MGAM2 Q2M2H8 1/20 1.00
▸ MAOA P21397 1/20 0.65
▸ NPC1 O15118 2/20 0.57
▸ HIF1A Q16665 3/20 0.57
▸ KDM4E B2RXH2 10/20 0.56
▸ ALDH1A1 P00352 10/20 0.56
▸ HPGD P15428 10/20 0.56
▸ HSD17B10 Q99714 6/20 0.56
▸ MAPT P10636 3/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ CA9 Q16790 3/20 0.48
▸ CA12 O43570 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decursinol SCHEMBL14105325 1.00 GAA (1.00) GAAACHEMGAMSIPTPN1
Decursinol SCHEMBL3895912 1.00 GAA (1.00) GAAACHEMGAMSIPTPN1
Decursinol SCHEMBL29517185 1.00 GAA (1.00) GAAACHEMGAMSIPTPN1
Decursinol SCHEMBL18845442 1.00 GAA (1.00) GAAACHEMGAMSIPTPN1
SCHEMBL14105337 0.86 GAA (0.76) GAAACHEMGAMSIPTPN1
SCHEMBL23983278 0.83 GAA (0.71) GAAACHEMGAMSIPTPN1
SCHEMBL14303567 0.82 MAOA (0.79) GAAACHEMGAMSIPTPN1
SCHEMBL4740846 0.82 MAOA (0.79) GAAACHEMGAMSIPTPN1
SCHEMBL15444405 0.80 MAOA (0.67) GAAACHEMGAMSIPTPN1
Decursin SCHEMBL14511556 0.80 MAOA (1.00) GAAACHEMGAMSIPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 — — EP disclosed
EP-3617211-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING AGING-RELATED DISEASES CONTAINING DECURSIN DERIVATIVE AS ACTIVE INGREDIENT PRG S&TECH INC (KR) 2025-10-22 — — EP disclosed
US-12391704-B2 Method for synthesizing decursin derivative PRG S&TECH INC. (KR) 2025-08-19 — — US disclosed
EP-4083045-B1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&TECH INC (KR) 2023-12-13 — — EP disclosed
US-20230063754-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&TECH INC. (KR) 2023-03-02 — — US disclosed
EP-4083045-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&Tech Inc. (KR) 2022-11-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391704-B2 Method for synthesizing decursin derivative DHPS, NISCH, DOHH GAA 4779/4885ACHE 4626/4885MGAM 4471/4885
US-20230063754-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE DHPS, NISCH, NMUR2 GAA 4752/4885ACHE 4657/4885MGAM 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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