Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551811 | 1.00 | RPS6KA5 (0.47) | RPS6KA5NPC1ADORA2AMBNL1MAPT | |
| SCHEMBL15944113 | 0.87 | NPC1 (0.43) | RPS6KA5NPC1ADORA2AMBNL1MAPT | |
| SCHEMBL30036941 | 0.83 | KMT2A (0.46) | NPC1ADORA2AMBNL1MAPTL3MBTL1 | |
| SCHEMBL25551813 | 0.83 | KMT2A (0.46) | NPC1ADORA2AMBNL1MAPTL3MBTL1 | |
| SCHEMBL25559456 | 0.83 | NPC1 (0.40) | RPS6KA5NPC1ADORA2AMBNL1MAPT | |
| SCHEMBL25552004 | 0.83 | MBNL1 (0.51) | NPC1ADORA2AMBNL1MAPTPIN1 | |
| SCHEMBL30036507 | 0.81 | KMO (0.47) | NPC1ADORA2AADORA1 | |
| SCHEMBL25551806 | 0.81 | KMO (0.47) | NPC1ADORA2AADORA1 | |
| SCHEMBL30919844 | 0.79 | HTR5A (0.43) | RPS6KA5NPC1ADORA2AADORA1PTGS2 | |
| SCHEMBL30891600 | 0.79 | RPS6KA5 (0.47) | RPS6KA5MAPTL3MBTL1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |