Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426744 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TDP1MTNR1AMTNR1BTSHR | |
| SCHEMBL2673221 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1MTNR1AMTNR1BTSHR | |
| SCHEMBL27942554 | 0.88 | MTNR1A (0.51) | ALDH1A1MTNR1AMTNR1BTSHRMEN1 | |
| SCHEMBL6695813 | 0.88 | MTNR1A (0.53) | ALDH1A1MTNR1AMTNR1BTSHRMEN1 | |
| SCHEMBL7057079 | 0.86 | MTNR1A (0.50) | ALDH1A1TDP1MTNR1AMTNR1BTSHR | |
| SCHEMBL20223077 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TDP1MTNR1AMTNR1BTSHR | |
| SCHEMBL17478028 | 0.84 | MTNR1A (0.50) | ALDH1A1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL5329552 | 0.83 | TDP1 (0.49) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL20212191 | 0.82 | CYP4F2 (0.45) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL28584327 | 0.82 | CYP1A2 (0.48) | ALDH1A1MTNR1AMTNR1BTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |