Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306711 | 0.92 | TDP1 (0.53) | TDP1MMP8EPHX2ALDH1A1TSHR | |
| SCHEMBL6688791 | 0.86 | PPARG (0.49) | ALDH1A1PPARGPPARAMEN1KMT2A | |
| SCHEMBL7058718 | 0.84 | TDP1 (0.50) | TDP1MMP8EPHX2ALDH1A1TSHR | |
| SCHEMBL6988601 | 0.84 | MMP8 (0.48) | TDP1MMP8EPHX2ALDH1A1TSHR | |
| SCHEMBL6587934 | 0.84 | KMT2A (0.47) | TDP1MMP8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3344661 | 0.84 | EPHX2 (0.47) | TDP1MMP8EPHX2ALDH1A1TSHR | |
| SCHEMBL2426744 | 0.83 | ALDH1A1 (0.46) | TDP1MMP8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16342382 | 0.83 | MMP8 (0.43) | TDP1MMP8EPHX2ALDH1A1TSHR | |
| SCHEMBL30036768 | 0.83 | ALDH1A1 (0.46) | TDP1MMP8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9165065 | 0.83 | PPARG (0.50) | ALDH1A1PPARGPPARAKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341707-B1 | PHENYLETHANOL ESTER OF ORTHO-CINNAMIC ACID, ITS PREPARATION AND USE AS FRAGRANCE COMPOUND | Consortium für elektrochemische Industrie GmbH (DE) | 1992-09-02 | — | — | EP | claimed |
| US-7943634-B2 | Substituted benzo[4,5]furo[3,2-c]pyridine derivatives as PDE 4 inhibitors | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-05-17 | — | — | US | disclosed |
| US-20090306082-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2009-12-10 | — | — | US | disclosed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| US-5559272-A | Aromatic compounds | FIRMENICH S.A. (CH) | 1996-09-24 | — | — | US | disclosed |
| US-5442124-A | Process for the preparation of novel aromatic compounds | FIRMENICH SA (CH) | 1995-08-15 | — | — | US | disclosed |
| WO-1995000114-A1 | TETRALINE® FORMATE ESTER AROMA CHEMICALS | UNION CAMP CORPORATION (US) | 1995-01-05 | — | — | WO | disclosed |
| US-5324875-A | Musk odor | FIRMENICH SA (CH) | 1994-06-28 | — | — | US | disclosed |
| US-5292719-A | Perfumes, colognes, soaps and cosmetics; musk aroma | UNION CAMP CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
| US-5185318-A | Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients | FIRMENICH S.A. (CH) | 1993-02-09 | — | — | US | disclosed |
| EP-0310745-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | ORION-YHTYMÄ OY (FI) | 1993-01-27 | — | — | EP | disclosed |
| US-5162588-A | Muky type odor; colognes, shaving lotions, soaps, bath gels, shampoos, hair care products | FIRMENICH S.A. (CH) | 1992-11-10 | — | — | US | disclosed |
| US-5066640-A | Perfume with a floral scent | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1991-11-19 | — | — | US | disclosed |
| EP-0183492-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1989-11-15 | — | — | EP | disclosed |
| EP-0310745-A2 | Substituted imidazole derivatives and their preparation and use | ORION-YHTYMÄ OY (FI) | 1989-04-12 | — | — | EP | disclosed |
| US-4689339-A | 4-dihydroinden-2-yl-, 4-tetrahydronaphth-2-yl-, and 4-dihydrobenzofuran-2-ylimidazoles, useful to block α2 -adrenergic receptors | FARMOS YHTYMA OY (FI) | 1987-08-25 | — | — | US | disclosed |
| EP-0183492-A1 | Substituted imidazole derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1986-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306082-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PTGER4, NOX4, PDE4A | TDP1 1450/4885MMP8 41/4885EPHX2 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.