SCHEMBL30037495

SCHEMBL30037495

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.52
▸ CCKBR P32239 6/20 0.50
▸ KISS1R Q969F8 2/20 0.49
▸ CCKAR P32238 1/20 0.49
▸ GHSR Q92847 1/20 0.49
▸ C5AR1 P21730 1/20 0.49
▸ IL23R Q5VWK5 1/20 0.49
▸ CTSL P07711 2/20 0.48
▸ CTSS P25774 2/20 0.48
▸ CTSK P43235 2/20 0.48
▸ CTSH P09668 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037518 0.94 IL23R (0.53) MC4RCCKBRCCKARIL23RCTSL
SCHEMBL30264577 0.93 MC4R (0.52) MC4RKISS1RGHSRC5AR1IL23R
SCHEMBL31016486 0.92 CTSL (0.55) MC4RCCKBRCCKARC5AR1IL23R
SCHEMBL29476447 0.91 MC4R (0.50) MC4RCCKBRKISS1RCCKARGHSR
SCHEMBL29476484 0.91 MC4R (0.50) MC4RCCKBRKISS1RCCKARGHSR
SCHEMBL31016482 0.89 CTSL (0.54) GHSRC5AR1IL23RCTSLCTSS
SCHEMBL30676242 0.89 CTSL (0.53) MC4RKISS1RGHSRC5AR1IL23R
SCHEMBL29517075 0.89 C5AR1 (0.54) MC4RGHSRC5AR1IL23R
SCHEMBL31555133 0.88 MC4R (0.52) MC4RKISS1RGHSRC5AR1
SCHEMBL29419493 0.88 MC4R (0.52) MC4RKISS1RGHSRC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US claimed
EP-4347019-A1 MC3R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-04-10 — — EP claimed
WO-2022251650-A1 MC3R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-12-01 — — WO claimed
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US disclosed
EP-4347019-A1 MC3R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-04-10 — — EP disclosed
WO-2022251650-A1 MC3R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-12-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287154-A1 MC3R AGONIST PEPTIDES MC3R, MC4R, MC1R MC4R 2/4885CCKBR 83/4885KISS1R 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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