Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037130 | 0.90 | MBNL1 (0.47) | DHODHMBNL1HTR5ACSNK2A2CSNK2B | |
| SCHEMBL25552003 | 0.90 | MBNL1 (0.47) | DHODHMBNL1HTR5ACSNK2A2CSNK2B | |
| SCHEMBL30035813 | 0.88 | HTR5A (0.43) | DHODHMBNL1HTR5AADORA2ANPC1 | |
| SCHEMBL25551942 | 0.80 | KMO (0.42) | DHODHMBNL1KMO | |
| SCHEMBL30037152 | 0.80 | KMO (0.42) | DHODHMBNL1KMO | |
| SCHEMBL30036507 | 0.79 | KMO (0.47) | DHODHCSNK2A2CSNK2BADORA2ANPC1 | |
| SCHEMBL25551806 | 0.79 | KMO (0.47) | DHODHCSNK2A2CSNK2BADORA2ANPC1 | |
| SCHEMBL30036500 | 0.78 | HTR5A (0.48) | DHODHMBNL1HTR5ANPC1RAB9A | |
| SCHEMBL30036976 | 0.76 | MBNL1 (0.43) | DHODHMBNL1HTR5AADORA2ANPC1 | |
| SCHEMBL25552011 | 0.76 | MBNL1 (0.43) | DHODHMBNL1HTR5AADORA2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |