Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535847 | 1.00 | HCAR3 (0.44) | HCAR3SLC22A12KDM4ECSNK2A1MAT2A | |
| SCHEMBL23535848 | 0.84 | ALDH1A1 (0.41) | KDM4EHPGDALDH1A1 | |
| SCHEMBL30040748 | 0.84 | ALDH1A1 (0.41) | KDM4EHPGDALDH1A1 | |
| SCHEMBL30159550 | 0.81 | HCAR3 (0.36) | HCAR3SLC22A12KDM4ECSNK2A1RORC | |
| SCHEMBL23535658 | 0.81 | HCAR3 (0.36) | HCAR3SLC22A12KDM4ECSNK2A1RORC | |
| SCHEMBL17785249 | 0.80 | HCAR3 (0.47) | HCAR3SLC22A12KDM4EHPGDALDH1A1 | |
| SCHEMBL4509480 | 0.80 | SLC22A12 (0.57) | HCAR3SLC22A12KDM4E | |
| SCHEMBL30040324 | 0.80 | SLC22A12 (0.57) | HCAR3SLC22A12KDM4E | |
| SCHEMBL23559591 | 0.78 | HCAR3 (0.46) | HCAR3SLC22A12KDM4EHPGDALDH1A1 | |
| SCHEMBL31632926 | 0.78 | HCAR3 (0.46) | HCAR3SLC22A12KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-115427035-A | ENL/AF9YEATS inhibitors | 洛克菲勒大学 | 2022-12-02 | — | — | CN | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |