SCHEMBL30042017

SCHEMBL30042017

OCc1cc2cc(C(F)(F)F)ccc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.45
HRH4 Q9H3N8 1/20 0.44
KIF11 P52732 6/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
AR P10275 1/20 0.39
KDM4E B2RXH2 1/20 0.38
KLKB1 P03952 1/20 0.38
MAP4K1 Q92918 1/20 0.38
LOXL2 Q9Y4K0 2/20 0.38
METAP2 P50579 1/20 0.38
RHEB Q15382 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16619194 1.00 NR3C1 (0.45) NR3C1HRH4KIF11MEN1KMT2A
SCHEMBL23932536 0.86 METAP2 (0.45) NR3C1KIF11METAP2
SCHEMBL13365139 0.83 SCN10A (0.43) NR3C1KIF11LOXL2RHEB
SCHEMBL22996085 0.83 NR3C1 (0.45) NR3C1HRH4KIF11MEN1KMT2A
SCHEMBL17027129 0.78 F2 (0.55) NR3C1KIF11HDAC2
SCHEMBL5330339 0.77 KDM4E (0.51) NR3C1KDM4ERHEB
SCHEMBL27290612 0.77 HRH4 (0.47) HRH4KIF11MEN1KMT2AAR
SCHEMBL2216550 0.75 S1PR1 (0.46) NR3C1HRH4
SCHEMBL12096910 0.74 SRD5A2 (0.55) HRH4KLKB1MAP4K1HDAC2
SCHEMBL3529064 0.74 HRH4 (0.46) NR3C1HRH4ARKDM4EKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed