SCHEMBL16619194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30042017	1.00	NR3C1 (0.45)	NR3C1HRH4KIF11MEN1KMT2A
	SCHEMBL23932536	0.86	METAP2 (0.45)	NR3C1KIF11METAP2
	SCHEMBL13365139	0.83	SCN10A (0.43)	NR3C1KIF11LOXL2RHEB
	SCHEMBL22996085	0.83	NR3C1 (0.45)	NR3C1HRH4KIF11MEN1KMT2A
	SCHEMBL17027129	0.78	F2 (0.55)	NR3C1KIF11HDAC2
	SCHEMBL5330339	0.77	KDM4E (0.51)	NR3C1KDM4ERHEB
	SCHEMBL27290612	0.77	HRH4 (0.47)	HRH4KIF11MEN1KMT2AAR
	SCHEMBL2216550	0.75	S1PR1 (0.46)	NR3C1HRH4
	SCHEMBL12096910	0.74	SRD5A2 (0.55)	HRH4KLKB1MAP4K1HDAC2
	SCHEMBL3529064	0.74	HRH4 (0.46)	NR3C1HRH4ARKDM4EKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.