SCHEMBL300454

SCHEMBL300454

C=CCc1cccc2c1C(CC=C)c1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
HTR2A P28223 1/20 0.38
AKR1B1 P15121 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6300773 0.80 HTR2A (0.37) GABRA1GABRB2GAAKDM4ELMNA
SCHEMBL10774990 0.79 HTR2A (0.43) HTR2ACA1CA2
SCHEMBL17186645 0.79 HTR2A (0.39) HTR2ACA1CA2
SCHEMBL6682764 0.79 GABRA1 (0.46) GABRA1GABRB2GAAKDM4ELMNA
SCHEMBL252162 0.79 HTR2A (0.52) HTR2ACA1CA2
Hydrochloric Acid SCHEMBL8169416 0.78 HTR2A (0.38) KDM4EHTR2ACA1CA2
SCHEMBL8612084 0.78 HTR2A (0.38) HTR2ACA1CA2
Hydrochloric Acid SCHEMBL6720542 0.77 HTR2A (0.37) HTR2ACA1CA2
SCHEMBL8169417 0.76 HTR2A (0.36) HTR2A
SCHEMBL6720546 0.76 HTR2A (0.36) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10109796-B2 Methods of applying polymers to surfaces and surfaces coated by polymers SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2018-10-23 US claimed
US-9398927-B2 Medical implant SYNERGY BIOSURGICAL AG (CH) 2016-07-26 US claimed
EP-2181935-B1 Method of manufacturing an anti-static container SCHNEIDER EKKEHARD DIPL-ING (DE) 2016-06-22 EP claimed
US-8741392-B2 Anodically assisted chemical etching of conductive polymers and polymer composites INTEGRAN TECHNOLOGIES, INC. (CA) 2014-06-03 US claimed
EP-2654589-A1 KIT FOR IMPLANTING HEAT DEFORMABLE FIXATION ELEMENTS OF DIFFERENT SIZES Synthes GmbH (CH) 2013-10-30 EP claimed
WO-2012087426-A1 KIT FOR IMPLANTING HEAT DEFORMABLE FIXATION ELEMENTS OF DIFFERENT SIZES SYNTHES USA, LLC (US) 2012-06-28 WO claimed
US-20120157977-A1 Kit for Implanting Heat Deformable Fixation Elements of Different Sizes DEPUY SPINE, LLC 2012-06-21 US claimed
EP-2438220-A1 ANODICALLY ASSISTED CHEMICAL ETCHING OF CONDUCTIVE POLYMERS AND POLYMER COMPOSITES Integran Technologies Inc. (CA) 2012-04-11 EP claimed
US-20100311901-A1 ARAMID FILLED POLYIMIDES HAVING ADVANTAGEOUS THERMAL EXPANSION PROPERTIES, AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-09 US claimed
WO-2010139051-A1 ANODICALLY ASSISTED CHEMICAL ETCHING OF CONDUCTIVE POLYMERS AND POLYMER COMPOSITES INTEGRAN TECHNOLOGIES, INC. (CA) 2010-12-09 WO claimed
US-20060068211-A1 Low temperature polyimide adhesive compositions and methods relating thereto DUPONT ELECTRONICS, INC. 2006-03-30 US claimed
EP-1638666-A1 CONDUCTING GAS PURIFICATION FILTER AND FILTER ASSEMBLY NUTSOS, Mikael (SE) 2006-03-29 EP claimed
WO-2006031411-A2 A CONDUCTIVE LITHOGRAPHIC POLYMER MIXTURE AND METHOD OF MAKING DEVICES USING SAME INTEL CORPORATION (US) 2006-03-23 WO claimed
US-20060051707-A1 Conductive lithographic polymer and method of making devices using same INTEL CORPORATION 2006-03-09 US claimed
EP-1531657-A1 Multi-layer substrates having at least two dissimilar polyimide layers and a conductive layer, useful for electronics-type applications, and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2005-05-18 EP claimed
US-20050100719-A1 Vaiations in glass transition temperature between layers; electroconductive layer DUPONT ELECTRONICS, INC. 2005-05-12 US claimed
WO-2004096413-A1 CONDUCTING GAS PURIFICATION FILTER AND FILTER ASSEMBLY NUTSOS MIKAEL (SE) 2004-11-11 WO claimed
EP-1424352-A1 Low temperature polymide adhesive compositions and methods relating thereto E.I.Du pont de nemours and company (US) 2004-06-02 EP claimed
US-20040099374-A1 Low temperature polyimide adhesive compositions and methods relating thereto DUPONT ELECTRONICS, INC. 2004-05-27 US claimed
US-20020093283-A1 Luminescent device and method of manufacturing same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2002-07-18 US claimed