Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 5/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28514500 | 0.98 | PABPC1 (0.47) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Hydrochloric Acid SCHEMBL29143069 | 0.98 | PABPC1 (0.47) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Iodide SCHEMBL28963916 | 0.96 | PABPC1 (0.50) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Hydrochloric Acid SCHEMBL9243920 | 0.89 | TERT (0.49) | MAPTLMNATERTCHKACYP1A2 | |
| SCHEMBL10593608 | 0.86 | MEN1 (0.46) | MAPTLMNATERTCHKACYP1A2 | |
| SCHEMBL5710989 | 0.84 | MAPT (0.50) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Iodide SCHEMBL22491540 | 0.84 | CHKA (0.49) | MAPTLMNATERTCHKACYP1A2 | |
| Bromide SCHEMBL16339212 | 0.84 | CHKA (0.45) | MAPTLMNATERTCHKACYP1A2 | |
| Ethylene Glycol SCHEMBL28409752 | 0.83 | MAPT (0.69) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| SCHEMBL19892478 | 0.82 | MAPT (0.52) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260100415-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2026-04-09 | — | — | US | disclosed |
| US-12525646-B2 | Ionic cyclic nitroxyl radical oligomers | WISCONSIN ALUMINI RESEARCH FOUNDATION (US) | 2026-01-13 | — | — | US | disclosed |
| EP-4298090-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | Wisconsin Alumni Research Foundation (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20230006250-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-01-05 | — | — | US | disclosed |
| WO-2022251610-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260100415-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | NOX4, NOX1, CYBB | PABPC1 4163/4885APOBEC3A 866/4885EIF4H 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.