Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300549 | 0.86 | THRB (0.41) | CCR3POLB | |
| SCHEMBL176414 | 0.84 | NPC1 (0.44) | CNR1CNR2CCR3POLB | |
| SCHEMBL300546 | 0.84 | VIPR2 (0.36) | CNR1CNR2 | |
| SCHEMBL300472 | 0.84 | PDE9A (0.38) | CCR3POLB | |
| SCHEMBL300365 | 0.83 | CNR2 (0.41) | CNR1CNR2 | |
| SCHEMBL176833 | 0.83 | POLB (0.43) | CNR1CNR2CCR3POLB | |
| SCHEMBL300469 | 0.83 | CYP3A4 (0.40) | CNR2EPHX1 | |
| SCHEMBL300521 | 0.82 | CNR2 (0.43) | CNR2 | |
| SCHEMBL176941 | 0.82 | NPC1 (0.41) | CNR1CNR2CCR3POLB | |
| SCHEMBL300474 | 0.79 | EPHX2 (0.39) | CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |