SCHEMBL3004853

SCHEMBL3004853

CCNCO[SiH2]C=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.39
TRPA1 O75762 2/20 0.34
RAB9A P51151 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 1/20 0.34
THPO P40225 1/20 0.34
HIF1A Q16665 1/20 0.34
MTOR P42345 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
IDO1 P14902 2/20 0.33
GMNN O75496 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAOB P27338 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPK1 P28482 1/20 0.33
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1470879 0.80 RELA (0.48) RELATRPA1RAB9ACYP1A2CYP3A4
SCHEMBL1470882 0.80 RELA (0.48) RELATRPA1RAB9ACYP1A2CYP3A4
(Z)-1,2-Diphenylethene SCHEMBL9179151 0.73 RELA (0.52) RELATRPA1RAB9ACYP1A2CYP3A4
SCHEMBL2101117 0.71 RELA (0.36) RELATRPA1CYP1A2CYP3A4THPO
SCHEMBL1468386 0.70 TRPA1 (0.48) RELATRPA1CYP1A2CYP3A4ALDH1A1
SCHEMBL1468384 0.70 TRPA1 (0.48) RELATRPA1CYP1A2CYP3A4ALDH1A1
SCHEMBL8990017 0.69 MAOB (0.48) RELATRPA1CYP1A2LMNAALDH1A1
SCHEMBL2274711 0.69 RELA (0.40) RELATRPA1MAOBNPC1L3MBTL1
SCHEMBL28064246 0.69 RELA (0.41) RELATRPA1RAB9ACYP1A2CYP3A4
Diethylamine SCHEMBL9176360 0.69 TTR (0.48) RELATRPA1CYP3A4ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247504-B2 Catalyst component, catalyst for olefin polymerization, and process for producing olefin polymer using catalyst Toho Titanium, Co.,. Ltd. (JP) 2012-08-21 US claimed
EP-1921092-B1 CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER USING THOSE TOHO TITANIUM CO LTD (JP) 2013-10-02 EP disclosed
US-8247504-B2 Catalyst component, catalyst for olefin polymerization, and process for producing olefin polymer using catalyst Toho Titanium, Co.,. Ltd. (JP) 2012-08-21 US disclosed
US-20100190938-A1 CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER USING CATALYST TOHO TITANIUM CO., LTD. (JP) 2010-07-29 US disclosed
EP-1921092-A1 CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER USING THOSE Toho Catalyst Co., Ltd. (JP) 2008-05-14 EP disclosed