Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162064 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAHSD17B10L3MBTL1 | |
| SCHEMBL30051015 | 0.85 | NAMPT (0.49) | ALDH1A1NAMPTGAAHSD17B10L3MBTL1 | |
| SCHEMBL30049771 | 0.83 | NAMPT (0.55) | NAMPTF13A1TGM2TGM1GPR119 | |
| SCHEMBL16430912 | 0.82 | GPR119 (0.55) | ALDH1A1HSD17B10GPR119RETTSHR | |
| SCHEMBL27162435 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAHSD17B10L3MBTL1 | |
| SCHEMBL30049877 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAHSD17B10L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL27162673 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NAMPTGAAHSD17B10 | |
| SCHEMBL27161993 | 0.77 | CYP3A4 (0.58) | ALDH1A1SMN1; SMN2GAAHSD17B10TSHR | |
| SCHEMBL30050081 | 0.77 | CYP3A4 (0.58) | ALDH1A1SMN1; SMN2GAAHSD17B10TSHR | |
| SCHEMBL30050074 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254115-A1 | New Pyridine-Sulfonamide Derivatives as Sigma Ligands | ACONDICIONAMIENTO TARRASENSE (ES) | 2024-08-01 | — | — | US | disclosed |
| EP-4330248-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022229405-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254115-A1 | New Pyridine-Sulfonamide Derivatives as Sigma Ligands | SIGMAR1, TMEM97, OPRD1 | ALDH1A1 1011/4885SMN1; SMN2 3118/4885NAMPT 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.