Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23858844 | 1.00 | HCAR2 (0.44) | HCAR2GPR17PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL29324357 | 0.85 | GPR17 (0.35) | HCAR2GPR17PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL28496732 | 0.83 | GPR17 (0.45) | HCAR2GPR17PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23872474 | 0.81 | KDM4E (0.48) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL16240884 | 0.76 | CTNNB1 (0.44) | HCAR2PRKAG1PRKAA1PRKAB1PRKAB2 | |
| SCHEMBL4785188 | 0.75 | PRKAG1 (0.58) | HCAR2PRKAG1PRKAA1PRKAB1PRKAB2 | |
| SCHEMBL2955386 | 0.74 | MAP2K4 (0.37) | GPR17MAP2K4MAPK1MAPK6CA12 | |
| SCHEMBL2816583 | 0.72 | MAP2K4 (0.61) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL16517070 | 0.72 | PRKAB2 (0.34) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL5522246 | 0.71 | PRKAG1 (0.40) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335378-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4126860-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| CN-115335378-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-11 | — | — | CN | disclosed |