Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 9/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30408409 | 0.89 | NPBWR1 (0.46) | NPBWR1MCHR1UCHL1KDM4E | |
| SCHEMBL30050755 | 0.89 | PDE8B (0.46) | NPBWR1PTPN1MCHR1UCHL1 | |
| SCHEMBL30469042 | 0.81 | NPBWR1 (0.54) | NPBWR1MCHR1 | |
| SCHEMBL20176889 | 0.80 | NPBWR1 (0.47) | NPBWR1MCHR1KDM4E | |
| SCHEMBL14809708 | 0.78 | NPBWR1 (0.51) | NPBWR1PTPN1CHRM1MCHR1UCHL1 | |
| SCHEMBL20746001 | 0.78 | NPBWR1 (0.51) | NPBWR1PTPN1CHRM1MCHR1UCHL1 | |
| SCHEMBL29049972 | 0.77 | PTPN1 (0.60) | NPBWR1PTPN1CHRM1MCHR1UCHL1 | |
| SCHEMBL21579413 | 0.77 | NPBWR1 (0.44) | NPBWR1MCHR1UCHL1KDM4E | |
| SCHEMBL3356344 | 0.77 | MEN1 (0.52) | NPBWR1PTPN1CHRM1MCHR1UCHL1 | |
| SCHEMBL20177016 | 0.76 | NPBWR1 (0.44) | NPBWR1MCHR1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348453-A | Heteroaromatic carboxamide compounds and uses thereof | 烨辉医药科技(上海)有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022228302-A1 | HETEROAROMATIC CARBOXAMIDE COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2022-11-03 | — | — | WO | disclosed |