Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 9/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051137 | 0.89 | NPBWR1 (0.46) | NPBWR1UCHL1KDM4EMCHR1 | |
| SCHEMBL30050755 | 0.88 | PDE8B (0.46) | NPBWR1UCHL1MCHR1CYP11B1CYP11B2 | |
| SCHEMBL759935 | 0.83 | NPBWR1 (0.44) | NPBWR1UCHL1KDM4EALDH1A1GLA | |
| SCHEMBL30469042 | 0.80 | NPBWR1 (0.54) | NPBWR1MCHR1 | |
| SCHEMBL28320349 | 0.79 | PTGS2 (0.46) | NPBWR1KDM4EALDH1A1GLAGAA | |
| SCHEMBL23206336 | 0.79 | SMN1; SMN2 (0.52) | NPBWR1UCHL1KDM4EGAAMCHR1 | |
| SCHEMBL14810739 | 0.79 | UCHL1 (0.53) | NPBWR1UCHL1KDM4EALDH1A1GLA | |
| SCHEMBL20176889 | 0.79 | NPBWR1 (0.47) | NPBWR1KDM4EALDH1A1MCHR1LMNA | |
| SCHEMBL17895896 | 0.78 | NPBWR1 (0.49) | NPBWR1UCHL1KDM4EMCHR1LMNA | |
| SCHEMBL21458329 | 0.77 | NPBWR1 (0.44) | NPBWR1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348453-A | Heteroaromatic carboxamide compounds and uses thereof | 烨辉医药科技(上海)有限公司 | 2023-06-27 | — | — | CN | disclosed |