SCHEMBL30051651

SCHEMBL30051651

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nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 1/20 0.50
▸ ACE P12821 1/20 0.50
▸ CPA1 P15085 1/20 0.50
▸ ACE2 Q9BYF1 1/20 0.50
▸ SLC7A5 Q01650 1/20 0.44
▸ CTSD P07339 2/20 0.43
▸ ENPEP Q07075 14/20 0.43
▸ BACE1 P56817 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665623 0.96 MME (0.47) MMEACECPA1ACE2SLC7A5
SCHEMBL29351914 0.91 ALDH1A1 (0.50) SLC7A5CTSDENPEPALDH1A1
SCHEMBL38651899 0.90 CTSD (0.49) CTSDBACE1
SCHEMBL30052478 0.88 ALDH1A1 (0.47) MMEACECPA1ACE2SLC7A5
SCHEMBL29453382 0.88 CTSD (0.48) SLC7A5CTSDENPEPALDH1A1
SCHEMBL29598573 0.88 ENPEP (0.51) MMEACECPA1ACE2ENPEP
SCHEMBL9491298 0.88 ALDH1A1 (0.53) SLC7A5CTSDENPEPALDH1A1
SCHEMBL9491302 0.88 ALDH1A1 (0.53) SLC7A5CTSDENPEPALDH1A1
SCHEMBL16698375 0.88 ALDH1A1 (0.53) SLC7A5CTSDENPEPALDH1A1
SCHEMBL14941289 0.88 ALDH1A1 (0.53) SLC7A5CTSDENPEPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118666988-A Composition for synthesis Trizepatide and synthetic method of Trizepatide 深圳佳肽生物科技有限公司 2024-09-20 — — CN claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
CN-118666988-A Composition for synthesis Trizepatide and synthetic method of Trizepatide 深圳佳肽生物科技有限公司 2024-09-20 — — CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP MME 824/4885ACE 1190/4885CPA1 245/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD MME 105/4885ACE 486/4885CPA1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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