Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821378 | 0.85 | LIPG (0.47) | LPLLIPGHIF1AIRAK4ROCK1 | |
| SCHEMBL2558221 | 0.84 | LPL (0.41) | LPLLIPGHIF1A | |
| SCHEMBL26113775 | 0.82 | LIPG (0.44) | LPLLIPGHIF1AIRAK4 | |
| SCHEMBL27265290 | 0.82 | LIPG (0.44) | LPLLIPGHIF1AIRAK4 | |
| SCHEMBL23484493 | 0.81 | HIF1A (0.45) | LPLLIPGHIF1AIRAK4 | |
| SCHEMBL22290411 | 0.81 | DRD2 (0.44) | LPLLIPGDRD2HTR7SIGMAR1 | |
| SCHEMBL24363869 | 0.80 | QDPR (0.50) | LPLLIPGHIF1AROCK1 | |
| SCHEMBL30470277 | 0.80 | QDPR (0.50) | LPLLIPGHIF1AROCK1 | |
| SCHEMBL14313971 | 0.79 | USP30 (0.50) | — | |
| SCHEMBL15639001 | 0.79 | HRH3 (0.39) | LPLLIPGMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333982-A1 | PKC-THETA MODULATORS | Exscientia Al Limited (GB) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022234298-A1 | PKC-THETA MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |