SCHEMBL30064673

SCHEMBL30064673

COc1ccc(C(=O)/C=C/C2C=CC=CC2)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.54
MAPT P10636 6/20 0.53
TNFRSF1A P19438 1/20 0.53
PDE4A P27815 1/20 0.52
PDE4B Q07343 1/20 0.52
PDE4C Q08493 1/20 0.52
PDE4D Q08499 1/20 0.52
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
XDH P47989 1/20 0.50
MAPK1 P28482 2/20 0.47
USP2 O75604 1/20 0.47
TLR9 Q9NR96 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 2/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937965 0.80 ABCG2 (0.54) ABCG2MAPTMEN1KMT2AMAPK1
SCHEMBL4742843 0.77 MAOA (0.47) ABCG2MAPTMEN1KMT2AMAPK1
SCHEMBL28098802 0.74 CYP3A4 (0.48) ABCG2MAPTMEN1KMT2AMAPK1
SCHEMBL14416836 0.73 ABCG2 (0.72) ABCG2MAPTTNFRSF1APDE4APDE4B
SCHEMBL1726767 0.73 AURKA (0.38) ABCG2MAPTTNFRSF1AL3MBTL1CYP1A1
SCHEMBL4456573 0.72 ABCG2 (0.76) ABCG2MAPTTNFRSF1APDE4APDE4B
SCHEMBL4456570 0.72 ABCG2 (0.76) ABCG2MAPTTNFRSF1APDE4APDE4B
SCHEMBL4655610 0.71 ABCG2 (0.52) ABCG2MAPTMEN1KMT2ANPC1
SCHEMBL16616648 0.70 ABCG2 (0.72) ABCG2MAPTTNFRSF1APDE4APDE4B
SCHEMBL16616651 0.70 ABCG2 (0.72) ABCG2MAPTTNFRSF1APDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. PONTIFICIA UNIV CATOLICA DE VALPARAISO (CL) 2024-11-14 US claimed
WO-2022221968-A1 COMPOSITIONS COMPRISING RESINOUS EXUDATE METABOLITES FROM PLANTS OF THE GENUS ADESMIA, USED TO CONTROL AND TREAT INFECTIONS IN PLANT CROPS; AND METHODS FOR CONTROLLING INFECTIONS IN PLANT CROPS PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO (CL) 2022-10-27 WO claimed
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. PONTIFICIA UNIV CATOLICA DE VALPARAISO (CL) 2024-11-14 US disclosed
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. PONTIFICIA UNIV CATOLICA DE VALPARAISO (CL) 2024-11-14 US disclosed
WO-2022221968-A1 COMPOSITIONS COMPRISING RESINOUS EXUDATE METABOLITES FROM PLANTS OF THE GENUS ADESMIA, USED TO CONTROL AND TREAT INFECTIONS IN PLANT CROPS; AND METHODS FOR CONTROLLING INFECTIONS IN PLANT CROPS PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO (CL) 2022-10-27 WO disclosed
WO-2022221968-A1 COMPOSITIONS COMPRISING RESINOUS EXUDATE METABOLITES FROM PLANTS OF THE GENUS ADESMIA, USED TO CONTROL AND TREAT INFECTIONS IN PLANT CROPS; AND METHODS FOR CONTROLLING INFECTIONS IN PLANT CROPS PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO (CL) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. ERG28, RXFP4, CROCC ABCG2 1093/4885MAPT 4500/4885TNFRSF1A 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.