SCHEMBL4742843

SCHEMBL4742843

COc1cc(O)c(C(=O)C=CC2C=CC=CC2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP19A1 P11511 1/20 0.47
SLC5A1 P13866 1/20 0.44
SLC5A2 P31639 1/20 0.44
ABCG2 Q9UNQ0 6/20 0.43
NFKB1 P19838 1/20 0.41
DPP4 P27487 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
CYP3A4 P08684 6/20 0.41
MAPT P10636 4/20 0.41
KMT2A Q03164 3/20 0.41
TP53 P04637 2/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937965 0.93 ABCG2 (0.54) MAOAMAOBCYP2C9CYP2C19ABCG2
SCHEMBL2493332 0.88 MEN1 (0.42) MAOAMAOBCYP2C9CYP2C19CYP19A1
SCHEMBL1938572 0.86 MAPT (0.50) MAOAMAOBCYP2C9CYP2C19SLC5A1
SCHEMBL5084410 0.80 MAOA (0.45) MAOAMAOBCYP2C9CYP2C19CYP19A1
SCHEMBL23849510 0.79 ABCB1 (0.41) ABCB1
SCHEMBL1726653 0.78 MAPT (0.37) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL30064673 0.77 ABCG2 (0.54) ABCG2CYP3A4MAPTKMT2AHSD17B10
SCHEMBL4742903 0.76 CYP3A4 (0.37) CYP3A4MAPTUSP2
SCHEMBL1844264 0.76 ABCB1 (0.34) ABCB1
SCHEMBL28098802 0.74 CYP3A4 (0.48) MAOAMAOBCYP2C9CYP2C19CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10695283-B2 Extract of Greyia radlkoferi and use thereof UNIVERSITY OF PRETORIA (ZA) 2020-06-30 US claimed
US-20180071204-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF KWAZULU-NATAL (ZA) 2018-03-15 US claimed
EP-2849768-B1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIV PRETORIA (ZA) 2016-06-01 EP claimed
US-20150118337-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2015-04-30 US claimed
US-12569530-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-03-10 US disclosed
US-12453799-B1 Bioadhesive for medical and dental applications IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-10-28 US disclosed
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-08-07 US disclosed
US-12318422-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-06-03 US disclosed
US-20240293492-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-09-05 US disclosed
US-20230210931-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-07-06 US disclosed
US-11376570-B1 Method of forming copper oxide-on-copper nanomaterial catalyst mesh KING ABDULAZIZ UNIVERSITY (SA) 2022-07-05 US disclosed
US-11311492-B1 Carbon nanomedicine with natural ligands KING ABDULAZIZ UNIVERSITY (SA) 2022-04-26 US disclosed
US-20150118337-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2015-04-30 US disclosed
CN-104582713-A Grignard family feijie extract and application thereof UNIV PRETORIA 2015-04-29 CN disclosed
EP-2849768-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF University of Pretoria (ZA) 2015-03-25 EP disclosed
EP-2849768-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF University of Pretoria (ZA) 2015-03-25 EP disclosed
US-20140023721-A1 METHOD OF EXTRACTING ACTIVE MOLECULES FROM NATURAL RESINS AND USE THEREOF RODE PHARMA S.R.L. (IT) 2014-01-23 US disclosed
WO-2013171720-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2013-11-21 WO disclosed
WO-2013171720-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2013-11-21 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER UGGT1, G6PD, UGT1A3 MAOA 3217/4885MAOB 4135/4885CYP2C9 1260/4885
US-20240293492-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL UGGT1, G6PD, UGDH MAOA 3285/4885MAOB 4088/4885CYP2C9 2611/4885
US-12569530-B2 Tannin-based antiproliferative pharmaceutical SLC2A3, SLC2A1, SLC2A8 MAOA 3606/4885MAOB 4076/4885CYP2C9 1523/4885
US-20230210931-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL UGGT1, G6PD, UGDH MAOA 3285/4885MAOB 4088/4885CYP2C9 2611/4885
US-12318422-B2 Tannin-based antiproliferative pharmaceutical UGGT1, G6PD, UGDH MAOA 3285/4885MAOB 4088/4885CYP2C9 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.