Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753297 | 1.00 | PARP10 (0.53) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL355820 | 0.96 | MAOA (0.53) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL29483386 | 0.96 | MAOA (0.53) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL16230083 | 0.88 | TDP1 (0.63) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL29804236 | 0.88 | PBRM1 (0.64) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL27286 | 0.88 | PBRM1 (0.64) | PARP10TDP1L3MBTL1PARP1PBRM1 | |
| SCHEMBL29521431 | 0.84 | MAOA (0.59) | PARP10MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL2065611 | 0.84 | MAOA (0.59) | PARP10MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL570706 | 0.84 | MAOA (0.59) | PARP10MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL5145478 | 0.80 | PBRM1 (0.78) | PBRM1MAOAMAOBCYP2A6PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746064-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF ACUTE BRAIN INJURY | UNIV COPENHAGEN (DK) | 2025-04-16 | — | — | EP | disclosed |
| US-20240391865-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY | OTAGO INNOVATION LIMITED (NZ) | 2024-11-28 | — | — | US | disclosed |
| US-12077495-B2 | Compounds for the treatment of acute brain injury | Københavns Universitet (DK) | 2024-09-03 | — | — | US | disclosed |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| WO-2022218311-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | APPICINE THERAPEUTICS (HK) LIMITED (CN) | 2022-10-20 | — | — | WO | disclosed |
| US-20210122700-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY | UNIVERSITY OF OTAGO (NZ) | 2021-04-29 | — | — | US | disclosed |
| EP-2704571-B1 | AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-2704571-B1 | AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3242872-B1 | (PIPERIDIN-3-YL)(NAPHTHALEN-2-YL)METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HISTONE DEMETHYLASE KDM2B FOR THE TREATMENT OF CANCER | GENENTECH INC (US) | 2019-07-03 | — | — | EP | disclosed |
| EP-3242872-B1 | (PIPERIDIN-3-YL)(NAPHTHALEN-2-YL)METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HISTONE DEMETHYLASE KDM2B FOR THE TREATMENT OF CANCER | GENENTECH INC (US) | 2019-07-03 | — | — | EP | disclosed |
| WO-2004069832-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004069244-A1 | OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| US-5753655-A | PROGESTINS OR ANTIPROGESTINS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997017332-A1 | 1-ARYLSULPHONYL, ARYL(THIO)CARBONYL PYRIDAZINO DERIVATIVES AND METHODS OF PREPARATION | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077495-B2 | Compounds for the treatment of acute brain injury | F2R, F2RL3, ARG2 | PARP10 593/4885TDP1 3895/4885L3MBTL1 3126/4885 |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | BCL2, BCL2L2, BCL2L1 | PARP10 1868/4885TDP1 3955/4885L3MBTL1 2022/4885 |
| US-20210122700-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY | F2R, F2RL3, ARG2 | PARP10 702/4885TDP1 3992/4885L3MBTL1 3229/4885 |
| US-20240391865-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY | F2R, F2RL3, ARG2 | PARP10 702/4885TDP1 3992/4885L3MBTL1 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.